By Catherine Marcucci, Michael P. Hutchens et al. (eds.)
The prevalence of deleterious or perhaps deadly drug-drug interactions (DDIs) within the perioperative interval isn't any longer a theoretical situation yet a harrowing fact. A Case method of Perioperative Drug-Drug Interactions addresses the complicated realm of pharmacokinetic drug interactions in an easy-to-read quantity that capabilities as either a accomplished medical reference and a casebook. The ebook offers a precis of the center options of drug interactions; an geared up, annotated presentation of the drug interactions so much proper to the perioperative clinician; and nearly two hundred case eventualities that spotlight particular drug interactions. This booklet fills a true void within the scientific literature and is necessary to anesthesiologists and surgeons, in addition to trainees in either specialties; in depth care employees, together with physicians, physician’s assistants, and nurses; and nurse practitioners who employees preoperative overview clinics.
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Additional info for A Case Approach to Perioperative Drug-Drug Interactions
Lum, RN, BSN, CCRN-CSC Cardiac and Surgical Intensive Care Unit, Oregon Health and Science University, Portland, OR, USA Elizabeth Macri, MD Department of Neurology, Presbyterian Medical Group, Albuquerque, NM, USA Michael Mangione, MD Department of Anesthesiology, University of Pittsburgh School of Medicine, VA Pittsburgh Healthcare System, Pittsburgh, PA, USA Ana Maria Manrique, MD Department of Anesthesiology, Children’s Hospital of Pittsburgh, Pittsburgh, PA, USA Catherine Marcucci, MD Anesthesia Services Department, Philadelphia Veterans Affairs Medical Center, Philadelphia, PA, USA Joško Markić, MD, MSc Pediatric Intensive Care Unit, Department of Pediatrics, University Hospital of Split, Split, Croatia Koshy M.
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This is how and where drugs are metabolized. These enzymes can also be inhibited and induced by medications, foods, and other substances, such as smoked tobacco. We have also included a short discussion of uridine 5′-diphospho-glucuronosyl transferases (UGTs), which is a family of enzymes much like the P450 enzymes that does the work of conjugative (Phase II) metabolism. P-glycoprotein and OATP Transporters is a short and easy-to-understand section that introduces two main drug transport systems that factor heavily in DDIs involving absorption.
A Case Approach to Perioperative Drug-Drug Interactions by Catherine Marcucci, Michael P. Hutchens et al. (eds.)